Table 1.
Mean hormone and semen parameters at baseline and after three months.
| Variable | Fertility Control baseline n = 9 | Infertility Treatment baseline n = 12 | Fertility Control 3 months n = 9 | Infertility Treatment 3 months n = 12 |
|---|---|---|---|---|
| Mean (±SD) | Mean (±SD) | Mean (±SD) | Mean (±SD) | |
| Median (1st, 3rd Q.) | Median (1st, 3rd Q.) | Median (1st, 3rd Q.) | Median (1st, 3rd Q.) | |
| Age (years) | 39.11 (3.02) | 35.83 (4.15) | 39.11 (3.02) | 35.83 (4.24) |
| 38 (37, 40) | 35.5 (33.75, 37.25) | 38 (37, 40) | 35.5 (33.75, 37.3) | |
| Seminal vol (mL) | 3.12 (1.59) | 2.73 (1.39) | 2.82 (1.71) | 2.93 (1.22) |
| 2.1 (2, 4) | 3 (1.8, 4) | 2 (2, 3) | 3 (2, 3) | |
| Sperm concentration (million/mL) | 70 (37.39) | 3.03 (2.49) | 79.44 (54.85) | 5.59 (6.71) |
| 50 (43, 111.3) | 2 (1, 4) | 55 (40, 100) | 2.5 (0.88, 10.25) | |
| Motility (%) | 61.34 (20.98) | 13.12 (8.27) | 47.22 (10.03) | 13.95 (10.39) |
| 55 (45.8, 67) | 12.5 (5, 20) | 45 (40, 60) | 12.5 (5.7, 20) | |
| Immotility (%) | 38.66 (20.98) | 86.88 (8.27) | 52.78 (10.03) | 86.05 (10.39) |
| 45 (33, 54.2) | 87.5 (80, 95) | 55 (40, 60) | 87.5 (80, 94.3) | |
| FSH (IU/mL) | 3.01 (0.7) | 5.79 (2.64) | 3.33 (1.16) | 7.97 (3.18) |
| 3.1 (2.5, 3.4) | 5.5 (3.6, 7.67) | 2.9 (2.6, 4.1) | 7.75 (5.67, 8.8) | |
| LH (IU/mL) | 4.92 (2.23) | 4.79 (2.43) | 4.81 (1.12) | 4.58 (2.24) |
| 4.6 (4.3, 6.1) | 4.3 (2.67, 6.85) | 4.9 (4.1, 5.3) | 4.35 (2.77, 5.35) | |
| Estradiol (pg/mL) | 18.67 (8.46) | 29.25 (13.89) | 20.89 (10.13) | 26.25 (8.47) |
| 16 (12, 23) | 25 (19, 37) | 21 (16, 28) | 26.5 (17.75, 32.3) | |
| Total Testosterone (ng/mL) | 4.99 (1.4) | 4.9 (1.45) | 4.99 (1.61) | 5.01 (1.49) |
| 4.75 (4.2, 5.7) | 5.06 (3.88, 5.76) | 4.7 (3.84, 6.3) | 5.57 (4.19, 5.84) | |
| Bioavailable testosterone (ng/mL) | 2.13 (0.53) | 2.47 (0.84) | 2.08 (0.5) | 2.32 (0.64) |
| 2.06 (1.9, 2.2) | 2.46 (1.98, 2.77) | 1.9 (1.75, 2.1) | 2.41 (1.8, 2.71) |
Hormone, semen and sperm parameters. The mean ± SD values for age (years), seminal volume (mL), sperm concentration (million/mL), motility (%), immotility (%), FSH (IU/mL), LH (IU/mL), estradiol (pg/mL), and testosterone (ng/mL). The fertile control and infertile treatment for baseline and after 3 months is presented with n-value indicated for each. In order to compare both groups, a numerical descriptive analysis has been made using the mean with standard deviation and the median (1st and 3rd quartile). The baseline differences between the treatment group and the control were then compared, as well as the effect of FSH between before and after treatment in the treated group. For this, mixed linear regression models were used in the case several measures per patient (semen volume and sperm concentration), and in the case of motility a beta logistic regression model was performed given its percentage character. The mixed models control the non-independence of data given that there are several measures per patient.