Fig. 1.

Transplanted MGE cells migrate and express markers of inhibitory neurons. a Hippocampus of CCI-injured recipients 30 DAT and 125 DAT labeled for DAPI (blue) and GFP+ transplanted neurons (green). MGE cells dispersed after grafting into recipient mice despite extensive hippocampal damage resulting from the contusion injury. b Distribution of transplanted MGE cells 30 DAT (blue, n = 3 TBI mice) and 125 DAT (pink, n = 3 TBI mice). F_(1,44) = 2.1 × 10⁻¹³; P = 0.99, two-way repeated measures ANOVA. c Quantification of marker expression of GFP-labeled cells in brain injured animals at 30 DAT (n = 3 mice per marker). CR calretinin, nNOS neuronal nitric oxide synthase, PV parvalbumin, SST somatostatin, VIP vasoactive intestinal peptide. d Representative confocal images in hippocampus (30 DAT) of staining for GFP (green) and molecular markers of inhibitory interneurons (magenta). Arrowheads, co-labeled cells; error bars, s.e.m.; scale bars, 500 μm (a) and 50 μm (d). Source data are provided as a Source Data file