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. 2019 Nov 14;9:16819. doi: 10.1038/s41598-019-53418-5

Figure 6.

Figure 6

Improvements in the neurological outcomes after OGD-PBMCs administration. (A) A significantly better functional recovery as assessed in the corner test (performed 20 times) was observed in the administration of the OGD-PBMC group compared with the vehicle-injected control group (PBS control group) and normoxic PBMC group at 28 days after cerebral ischemia; #P < 0.05 vs PBS control group (N = 6~8 per group). An absence of difference in functional recovery between the 5 × 105 normoxic PBMCs administration group and the PBS control group was seen. In addition, no functional recovery was observed in the administration of both the 1 × 105 OGD-monocytes (OGD-monocyte group) and 1 × 105 OGD-PBMCs, and PBS control (N = 5~6) groups by two-way ANOVA. (B) A significantly better functional recovery as assessed in the corner test was observed in the administration of the 18 h OGD-PBMC group compared with the PBS control group. Finally, an improvement in the administration of the 6 h OGD-PBMC group was not found; #P < 0.05 vs PBS control group by one-way ANOVA (N = 5~6).