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. Author manuscript; available in PMC: 2019 Nov 15.
Published in final edited form as: J Med Chem. 2019 Oct 31;62(21):9718–9731. doi: 10.1021/acs.jmedchem.9b01155

Figure 4.

Figure 4.

HL16 nonselectively suppressed the production of cytokines in vivo. Serum levels of IL-1β (A) and TNF-α (B) from C57BL/6 mice (n=4 per group) pretreated with HL16 (10 mg/kg) or MCC950 (10 mg/kg) by intraperitoneal injection (i.p.) were measured by ELISA 2.5 h after i.p. injection of LPS (50 mg/kg). Data are expressed as mean ± SD. Statistical analysis by student t-test.