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. Author manuscript; available in PMC: 2020 Nov 14.
Published in final edited form as: J Med Chem. 2019 Oct 28;62(21):9976–9982. doi: 10.1021/acs.jmedchem.9b01511

Table 1.

Serum IgG1 and IgG2a Anti-OVA Activity at Week 6a

entry adjuvant IgG1 (μg/mL) IgG2a (μg/mL) IgG2a/IgG1
1 none 113 ± 37 0.1 0.001**
2 GPI-0100 1,047 ± 292 166 ± 50 0.194 ± 0.060 (ns)
3 3 233 ± 74 0.2 <0.001**
4 4 262 ± 37 0.1 <0.001**
5 5 713 ± 293 208 ± 81 0.312 ± 0.126
6 6 869 ± 334 1 <0.001**
a

Values are expressed as the mean ± SEM. Statistical significance compared with OVA + 5:

*

P < 0.05.

**

P < 0.01.

***

P < 0.001.