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. Author manuscript; available in PMC: 2020 Nov 14.
Published in final edited form as: J Med Chem. 2019 Oct 28;62(21):9976–9982. doi: 10.1021/acs.jmedchem.9b01511

Table 2.

Acute Toxicity Comparison of 5, Quil A, and GPI-0100a

dose (μg) 5 GPI-0100b Quil-A
controls 5/5 5/5 5/5
100 5/5 S/S 0/5
200 5/5 5/5 0/5
500 5/5 5/5
1000 5/5 5/5
2000 5/5 4/5
5000 0/5 0/5
a

Results are expressed as the number of surviving mice per group of 5 mice 5 days after injection.

b

Literature results, female BALB/c mice of 16 weeks of age.31