Table 5.

Association of childhood physical and emotional abuse as measured by the CTQ with risk of incident SLE occurring after assessment of CTQ (2001) in the NHS II cohort (N=67,516)

CTQ Response	SLE Cases/person-years	Age and race-adjusted model HR (95% CI)	Parental and childhood-factor adjusted model* HR (95% CI)
None/Very low	4/190,651	Ref.	Ref.
Low	5/213,847	1.09 (0.29–4.07)	1.12 (0.30–4.20)
Moderate	13/258,615	2.38 (0.77–7.33)	2.33 (0.75–7.17)
High	14/200,449	3.14 (1.03–9.56)	3.11 (1.01–9.57)
p for trend		p=0.01	p=0.01

^*Model adjusted for age, race, maternal and paternal occupation, parental education, parental home ownership, birthweight, age at menarche, somatogram score at age 5