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. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: Neurocrit Care. 2020 Feb;32(1):162–171. doi: 10.1007/s12028-019-00734-3

Table 2.

Results of Longitudinal Multilevel Linear Regression

Heart Rate
Variability
Measures
Baseline Values Changes Over Time for NCI+
Beta Standard
Error
p-value Beta Standard
Error
p-value
MNN −0.10 0.018 <0.0001 0.00015 0.000016 <0.0001
SDNN −0.016 0.0045 0.0003 0.0000053 0.0000025 0.0354
CV −0.102 0.018 <0.0001 0.00028 0.000011 <0.0001
RMSSD −0.016 0.005 0.0022 −0.00001 0.0000029 <0.0001
SD1 −0.010 0.004 0.0194 0.0000094 0.0000017 <0.0001
SD2 −0.020 0.0048 <0.0001 0.0000028 0.0000033 0.4013
SD Ratio 0.079 0.031 0.0103 −0.00010 0.000030 0.0007
HFP −0.221 0.119 0.0646 0.00036 0.00012 <0.0001
LFP −0.185 0.233 0.4271 −0.0013 0.00029 0.0035
LHR 3.42 0.92 0.0002 −0.015 0.0011 <0.0001
DFA Alpha 1 −0.049 0.031 0.1132 0.0000061 0.000032 0.0560
DFA Alpha 2 0.0867 0.019 <0.0001 −0.00003 0.000043 0.4936

NCI = neurocardiogenic injury; MNN = mean of normal RR intervals; SDNN = mean of the standard deviations for all normal to normal RR intervals; CV = coefficient of variation of the RR interval time series; RMSSD = square root of the mean squared differences of successive NN intervals; SD1 = quantitative interpretation of Poincare plot and the standard deviation of the minor axis; SD2 = quantitative interpretation of Poincare plot and the standard deviation of the major axis; SD Ratio = SD1/SD2; HFP = high frequency power; LFP = low frequency power; LHR = LFP/HFP; DFA = detrended fluctuation analysis. For explanations of these terms, see Appendix B and C.