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Schematic illustration of the experimental setting. A) Stimulation of bone marrow-derived macrophages (BMDM) with lipopolysaccharide (LPS) in the presence and absence of 2% sevoflurane. B) Experimental setup for degradation of IκBα. C) In vitro update of FITC-labeled E. coli. D) In vivo inducible nitric oxide synthase (iNOS) expression and uptake of FITC-labeled E. coli by murine peritoneal macrophages.
