Table 1:

Molecular diagnoses for tumors with both imaging and methylation profiles available (n = 56)^a

PBL/ET	No.	Non-ET	No.
PBL	27	GBM_G34d	8
CNS_NB_FOXR2b	3	GBM_MYCNd	5
ETMRb	1	DMG_K27d	2
HGNET_MN1b	1	GBM_MIDd	2
MB_WNTb	1	EP_RELA	2
CNS ET, NOSb	1
ATRT_SHHc	2
ATRT_MYCc	1
Total	37		19

Note:—CNS_NB_FOXR2 indicates CNS neuroblastoma with FOXR2 activation; HGNET_MN1, CNS high-grade neuroepithelial tumor with MN1 alteration; MB_WNT: medulloblastoma with wingless (Wnt) activation; ATRT_SHH, atypical teratoid/rhabdoid tumor with sonic hedgehog (shh) activation; ATRT_MYC, atypical teratoid/rhabdoid tumor, subclass MYC; GBM_G34, glioblastoma, Isocitrate dehydrogenase (IDH) wild-type, H3.3 G34 mutant; GBM_MYCN, glioblastoma, IDH wild-type, subclass MYCN; DMG_K27, diffuse midline glioma H3K27M mutant; GBM-MID, glioblastoma, IDH wild-type, subclass midline; EP-RELA, ependymoma with positive RELA fusion.

^aFor further analysis, the following have been combined into single groups:

^bAs ET, other.

^cAs ATRT.

^dAs HGG.