Table 2. Clinical characteristics of risk factors for NEC (n=94).
Risk factors for NEC | Lactobacillus reuteri group (n=47) | Placebo group (n=47) | p-value | |
---|---|---|---|---|
Gestational age (wk) | 33 (28–34) | 33 (28–34) | 0.75 | |
Birth weight (g) | 1,520 (1,035–1,800) | 1,605 (1,060–1,800) | 0.73 | |
Cesarean section | 39 (83.0) | 40 (85.1) | 0.78 | |
Steroid administration | 35 (74.5) | 35 (74.5) | 1.00 | |
Length of steroid administration (d) | 2 (0–4) | 2 (0–2) | 0.16 | |
Asphyxia | 38 (80.9) | 42 (89.4) | 0.25 | |
Patent ductus arteriosus | 2 (4.3) | 3 (6.4) | 1.00 | |
APGAR score, 1 min | 7 (5–9) | 7 (3–9) | 0.72 | |
APGAR score, 5 min | 9 (6–10) | 9 (5–10) | 0.34 | |
Nutrition | ||||
Age at first feeding (d) | 2 (0–12) | 1 (0–14) | 0.79 | |
Predominant breast milk | 9 (19.1) | 10 (21.3) | 0.80 | |
Predominant preterm formula milk | 38 (80.9) | 37 (78.7) | - | |
Duration of total parenteral nutrition (d) | 8 (0–35) | 9 (0–69) | 0.52 | |
Time to reach full feeding (d) | 6 (0–25) | 7 (0–63) | 0.82 | |
Age at intervention (d) | 3 (0–18) | 4 (0–21) | 0.71 | |
Duration of intervention (d) | 21 (8–53) | 21 (7–66) | 0.78 |
Values are presented as mean (range) or number (%).
NEC: necrotizing colitis.