Table 2.
Predictors of 5-year survival rate using the method Kaplan-Meier and log-rank test
| Variables | Frequency, n (%) | 5-survival rate (%) | Median survival (month) | Log-rank test | P | |
|---|---|---|---|---|---|---|
| Alive patients (n=208) | Died patients (n=19) | |||||
| Age (year) | ||||||
| ≤60 | 62 (29.9) | 6 (31.5) | 8.80 | 13.2±3.1 | 1.68 | 0.23 |
| >60 | 146 (70.1) | 13 (68.5) | 8.10 | 12.5±3.4 | ||
| Sex | ||||||
| Female | 45 (21.7) | 4 (21.1) | 8.20 | 14.0±2.8 | 3.03 | 0.21 |
| Male | 163 (78.3) | 15 (78.9) | 8.12 | 12.4±3.01 | ||
| Family history | ||||||
| Negative | 193 (93) | 18 (94.7) | 8.94 | 12.77±4.8 | 3.24 | 0.19 |
| Positive | 15 (7) | 1 (5.3) | 9.10 | 11.5±2.8 | ||
| Tumor size (cm) | ||||||
| <1 | 54 (26) | 7 (36.8) | 11.50 | 18.7±6.1 | 6.24 | 0.001 |
| 1-3 | 87 (41.8) | 9 (47.5) | 9.30 | 12.22±4.2 | ||
| >3 | 67 (32.2) | 3 (15.7) | 4.20 | 8.1±3.4 | ||
| Metastasis | ||||||
| Absence | 102 (49) | 12 (63.1) | 10.50 | 16.1±5.8 | 5.31 | 0.021 |
| Presence | 66 (31.8) | 3 (25) | 4.20 | 9.2±4.11 | ||
| A known | 40 (19.2) | 4 (33.3) | 9 | 12.2±5.2 | ||
| n | ||||||
| ≤2 | 61 (29.3) | 13 (68.4) | 17.60 | 18.88±5.6 | 9.75 | 0.001 |
| >2 | 147 (70.7) | 6 (31.6) | 3.90 | 9.7±5.8 | ||
| Cirrhosis | ||||||
| Positive | 54 (26) | 4 (21) | 7.50 | 11.9±4.1 | 3.64 | 0.33 |
| Negative | 154 (74) | 15 (79) | 8.90 | 13.01±3.6 | ||
| Liver lobe | ||||||
| Right | 73 (35) | 6 (31.6) | 7.50 | 13.1±4.5 | 2.024 | 0.45 |
| Left | 38 (18.2) | 4 (21) | 9.70 | 13.5±4.3 | ||
| Both | 98 (46.8) | 9 (47.4) | 8.40 | 12.17±4.9 | ||
| serum AFP level (ng/mL) | ||||||
| <400 | 102 (49) | 9 (47.3) | 8.80 | 12.09±4.7 | 1.47 | 0.66 |
| ≥400 | 106 (51) | 10 (52.7) | 9.40 | 13.31±3.9 | ||
| Child-Pugh class | ||||||
| None | 54 (26) | 4 (21) | 6.90 | 13.5±4.12 | 0.684 | 0.51 |
| A | 121 (58.2) | 13 (68.4) | 9.70 | 12.3±4.13 | ||
| B | 19 (9.1) | 1 (5.3) | 5 | 11.8±3.2 | ||
| C | 14 (6.7) | 1 (5.3) | 6.60 | 10.4±3.16 | ||
| Treatment type | ||||||
| Surgery | 29 (13.9) | 2 (10.5) | 6.50 | 9.1±3.24 | 4.27 | 0.027 |
| Chemotherapy | 54 (26) | 4 (21.1) | 6.90 | 9.21±3.4 | ||
| Surgery + Chemotherapy | 78 (37.5) | 11 (57.9) | 12.40 | 18.05±4.6 | ||
| Other | 47 (22.6) | 2 (10.5) | 4.10 | 8.14±4.7 | ||
| Hepatitis type | ||||||
| None | 22 (10.6) | 4 (21) | 15.40 | 19.1±5.1 | 4.11 | 0.037 |
| HBV | 100 (48) | 9 (47.4) | 8.30 | 12.1±4.8 | ||
| HCV | 68 (32.7) | 6 (31.6) | 8.10 | 11.88±4.6 | ||
| HBV + HCV | 18 (3.7) | 0 (0) | 0 | 7.26±2.1 | ||
HBV=Hepatitis B virus; HCV=Hepatitis C virus; AFP=Alpha-fetoprotein