Table 2.
The baseline characteristics of MM patients in dataset GSE24080 between CHML-low group and CHML-high group.
| CHML-low | CHML-high | P-value | ||
|---|---|---|---|---|
| n | 381 | 178 | ||
| AGE (mean (sd)) | 56.74 (9.58) | 58.12 (9.16) | 0.108 | |
| SEX (%) | female | 144 (37.8) | 78 (43.8) | 0.206 |
| male | 237 (62.2) | 100 (56.2) | ||
| RACE (%) | other | 44 (11.5) | 18 (10.1) | 0.719 |
| white | 337 (88.5) | 160 (89.9) | ||
| ISOTYPE (%) | FLC | 59 (15.5) | 25 (14.0) | 0.89 |
| IgA | 85 (22.3) | 48 (27.0) | ||
| IgD | 2 ( 0.5) | 1 ( 0.6) | ||
| IgG | 218 (57.2) | 95 (53.4) | ||
| Nonsecretory | 4 ( 1.0) | 2 ( 1.1) | ||
| Unknown | 13 ( 3.4) | 7 ( 3.9) | ||
| B2M (mean (sd)) | 4.44 (5.24) | 5.34 (5.59) | 0.065 | |
| CRP (mean (sd)) | 10.38 (20.59) | 14.31 (27.30) | 0.06 | |
| CREAT (mean (sd)) | 1.30 (1.24) | 1.38 (1.35) | 0.49 | |
| LDH (mean (sd)) | 161.77 (51.71) | 193.81 (85.20) | <0.001 | |
| ALB (mean (sd)) | 4.08 (0.57) | 3.98 (0.60) | 0.059 | |
| HGB (mean (sd)) | 11.44 (1.77) | 10.85 (1.83) | <0.001 | |
| ASPC (mean (sd)) | 40.84 (23.97) | 46.65 (24.69) | 0.01 | |
| BMPC (mean (sd)) | 44.17 (26.34) | 51.06 (25.59) | 0.004 | |
| MRI (mean (sd)) | 10.60 (14.52) | 11.97 (14.55) | 0.317 | |
n, number of patients; sd, Standard deviation. CRP, C-reactive protein (mg/l); CREAT, Creatinine (mg/dl); LDH, Lactate dehydrogenase (U/l); ALB, Albumin (g/dl); HGB, Haemoglobin (g/dl) ; ASPC, Aspirate plasma cells (%). The statistical method used for SEX, RACE and ISOTYPE is Fisher's exact probability test, and others is unpaired t test (two sided).