Table 2.
SNP | Cases (%) | Controls (%) | P | OR (95% CI) | Pa |
---|---|---|---|---|---|
POT1 rs727505 | |||||
GG | 530 (52.2) | 543 (51.6) | 0.671 | 1.00 | |
AG | 409 (40.3) | 419 (39.8) | 1.01 (0.84-1.21) | 0.928 | |
AA | 76 (7.5) | 90 (8.6) | 0.86 (0.62-1.20) | 0.384 | |
AG/AA vs. GG | 0.785 | 0.98 (0.83-1.17) | 0.844 | ||
GG/AG vs. AA | 0.372 | 0.86 (0.63-1.18) | 0.357 | ||
POT1 rs727506 | |||||
GG | 262 (25.8) | 286 (27.2) | 0.473 | 1.00 | |
AG | 495 (48.8) | 522 (49.6) | 1.04 (0.84-1.28) | 0.736 | |
AA | 258 (25.4) | 244 (23.2) | 1.14 (0.90-1.46) | 0.289 | |
AG/AA vs. GG | 0.479 | 1.07 (0.88-1.30) | 0.501 | ||
GG/AG vs. AA | 0.238 | 1.11 (0.91-1.36) | 0.293 | ||
RTEL1 rs2297441 | |||||
GG | 433 (42.7) | 505 (48.0) | 0.019 | 1.00 | |
AG | 455 (44.8) | 446 (42.4) | 1.18 (0.98-1.412) | 0.080 | |
AA | 127 (12.5) | 101 (9.6) | 1.44 (1.08-1.93) | 0.014 | |
AG/AA vs. GG | 0.015 | 1.23 (1.03-1.46) | 0.021 | ||
GG/AG vs. AA | 0.035 | 1.33 (1.01-1.76) | 0.044 | ||
RTEL1 rs3208008 | |||||
AA | 419 (41.3) | 490 (46.6) | 0.034 | 1.00 | |
AC | 468 (46.1) | 454 (43.2) | 1.20 (1.00-1.44) | 0.055 | |
CC | 128 (12.6) | 108 (10.3) | 1.37 (1.03-1.83) | 0.033 | |
AC/CC vs. AA | 0.015 | 1.23 (1.03-1.46) | 0.020 | ||
AA/AC vs. CC | 0.094 | 1.25 (0.95-1.64) | 0.110 | ||
PARP1 rs1136410 | |||||
AA | 383 (37.7) | 374 (35.6) | 0.463 | 1.00 | |
AG | 473 (46.6) | 496 (47.1) | 0.93(0.77-1.12) | 0.438 | |
GG | 159 (15.7) | 182 (17.3) | 0.85 (0.66-1.10) | 0.215 | |
AG/GG vs. AA | 0.303 | 0.91 (0.76-1.09) | 0.284 | ||
AA/AG vs. GG | 0.317 | 0.887 (0.70-1.12) | 0.314 | ||
PARP1 rs1805414 | |||||
GG | 623 (61.4) | 663 (63.0) | 0.446 | 1.00 | |
AG | 335 (33.0) | 342 (32.5) | 1.05 (0.87-1.26) | 0.636 | |
AA | 57 (5.6) | 47 (4.5) | 1.29 (0.86-1.93) | 0.215 | |
AG/AA vs. GG | 0.441 | 1.08 (0.90-1.29) | 0.423 | ||
GG/AG vs. AA | 0.233 | 1.27 (0.85-1.89) | 0.238 |
aAdjusted for age and smoking status. The results were in bold if P < 0.05.