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. 2019 Oct 15;10(24):6170–6174. doi: 10.7150/jca.35917

Table 2.

Associations of Six SNPs with PCa Risk

SNP Cases (%) Controls (%) P OR (95% CI) Pa
POT1 rs727505
GG 530 (52.2) 543 (51.6) 0.671 1.00
AG 409 (40.3) 419 (39.8) 1.01 (0.84-1.21) 0.928
AA 76 (7.5) 90 (8.6) 0.86 (0.62-1.20) 0.384
AG/AA vs. GG 0.785 0.98 (0.83-1.17) 0.844
GG/AG vs. AA 0.372 0.86 (0.63-1.18) 0.357
POT1 rs727506
GG 262 (25.8) 286 (27.2) 0.473 1.00
AG 495 (48.8) 522 (49.6) 1.04 (0.84-1.28) 0.736
AA 258 (25.4) 244 (23.2) 1.14 (0.90-1.46) 0.289
AG/AA vs. GG 0.479 1.07 (0.88-1.30) 0.501
GG/AG vs. AA 0.238 1.11 (0.91-1.36) 0.293
RTEL1 rs2297441
GG 433 (42.7) 505 (48.0) 0.019 1.00
AG 455 (44.8) 446 (42.4) 1.18 (0.98-1.412) 0.080
AA 127 (12.5) 101 (9.6) 1.44 (1.08-1.93) 0.014
AG/AA vs. GG 0.015 1.23 (1.03-1.46) 0.021
GG/AG vs. AA 0.035 1.33 (1.01-1.76) 0.044
RTEL1 rs3208008
AA 419 (41.3) 490 (46.6) 0.034 1.00
AC 468 (46.1) 454 (43.2) 1.20 (1.00-1.44) 0.055
CC 128 (12.6) 108 (10.3) 1.37 (1.03-1.83) 0.033
AC/CC vs. AA 0.015 1.23 (1.03-1.46) 0.020
AA/AC vs. CC 0.094 1.25 (0.95-1.64) 0.110
PARP1 rs1136410
AA 383 (37.7) 374 (35.6) 0.463 1.00
AG 473 (46.6) 496 (47.1) 0.93(0.77-1.12) 0.438
GG 159 (15.7) 182 (17.3) 0.85 (0.66-1.10) 0.215
AG/GG vs. AA 0.303 0.91 (0.76-1.09) 0.284
AA/AG vs. GG 0.317 0.887 (0.70-1.12) 0.314
PARP1 rs1805414
GG 623 (61.4) 663 (63.0) 0.446 1.00
AG 335 (33.0) 342 (32.5) 1.05 (0.87-1.26) 0.636
AA 57 (5.6) 47 (4.5) 1.29 (0.86-1.93) 0.215
AG/AA vs. GG 0.441 1.08 (0.90-1.29) 0.423
GG/AG vs. AA 0.233 1.27 (0.85-1.89) 0.238

aAdjusted for age and smoking status. The results were in bold if P < 0.05.