Table 2.

Comparison of laboratory characteristics between responsive and non-responsive groups of PM/DM-ILD patients.

Clinical parameters	Responsive group (n = 11)	Non-responsive group (n = 7)	P-value
Lymphocytes, × 109/L, median (range)	0.69 (0.38–9.50)	0.60 (0.12–1.16)	0.285
CD4+/8+ T ratio, mean ± SEM	2.01 ± 0.58*	1.29 ± 0.87	0.049
Platelet count, × 109/L, mean ± SEM	224.819 ± 85.427	203.571 ± 91.874	0.894
Erythrocyte sedimentation rate, mm/h, median (range)	29 (2–105)	30 (1–64)	0.660
C-reactive protein, mg/L, mean ± SEM	6.506 ± 5.056*	15.281 ± 8.170	0.031
Serum ferritin, μg/L, median (range)	414.6 (78.1–3659.4)*	1518.6 (984.2–3819.2)	0.002
IL-6, pg/mL, median (range)	3.58 (0.07–35.50)	19.77 (5.99–832)	0.247
Procalcitonin (PCT), ng/mL, median (range)	0.710 (0.037–0.655)	0.125 (0.036–7.520)	0.151
Serum albumin (ALB), mg/L, mean ± SEM	31.960 ± 3.289	32.486 ± 3.023	0.204
Alanine aminotransferase (ALT), IU/L, median (range)	99 (20–142)	60 (26–439)	0.659
Aspartate aminotransferase (AST), IU/L, median (range)	64 (20–100.5)	60 (24–467)	0.860
Creatine kinase, IU/L, median (range)	80 (10–3,794)	83 (46–770)	0.930
Lactate dehydrogenase (LDH), IU/L, median (range)	412 (58–1,337)	491 (312–2,032)	0.375
Creatine, IU/L, mean ± SEM	54.82 ± 21.10	107.14 ± 128.4	0.325
Positive antinuclear antibody, n (%)	3(27.3)	0	0.245
Positive anti-Jo-1 antibody, n (%)	1(9.1)	0	0.611
Anti-SSA antibody, positivity, n (%)	7 (63.5)	5 (71.4)	1.000
Anti Ro-52 antibody, n (%)	7 (63.5)	4 (57.1)	1.000
Immunoglobulin A, mg/dL, median (range)	1.78 (1.39–3.55)	1.91 (0.72–3.65)	1.000
Immunoglobulin M, mg/dL, median (range)	1.45 (0.765–2.05)	1.100 (0.245–8.900)	0.425
Immunoglobulin G, mg/dL, mean ± SEM	14.84 ± 5.97	8.75 ± 6.15	0.894

^*p < 0.05. SEM, standard error of mean; ILD, interstitial lung disease; PM, polymyositis; DM, dermatomyositis.