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Effect of CRD mutation on binding pocket water occupancy.
| Protein | % of time within 3Å | SASA of Ca++ | |||
|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | ||
| WT | 100% | 100% | 4.92 ± 1.89 | ||
| E171A | 100% | 98% | 5.07 ± 2.32 | ||
| E195A | 100% | 73% | 73% | 67% | 27.74 ± 5.03 |
| R197A | 100% | 100% | 7.02 ± 1.62 | ||
| N214A | 10% | 98% | 6.12 ± 2.38 | ||
| D215A | 100% | 100% | 87% | 11.10 ± 2.57 | |
| X-Ray | + | + | |||
