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. 2019 Nov 8;7:271. doi: 10.3389/fcell.2019.00271

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Copyright © 2019 Cui, Wang, Liu, Liu, Zhang, Li, Zhu, Pan, Zhang and Cui.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The effect of ZFAS1 on tumor growth in vivo. (A) Representative image of Luciferase signal by a live imaging system. (B) Relative photon flux in sh-ZFAS1 group and sh-SCR group were quantified and analyzed using the IVIS imaging system. (C,D) Quantitative analysis of xenografted tumor volume and weight. (E,F) Representative hematoxylin and eosin (H&E) staining images and relative expression levels of immunohistochemical staining (IHC) for ki-67 in tumor sections from sh-ZFAS1 group and sh-SCR group. ^∗p < 0.05, ^∗∗p < 0.01, ^∗∗∗p < 0.001.