Figure 2.

Schematic showing possible integration of available tools for improved risk stratification to inform therapeutic strategy for an individual patient. Advances in next gen sequencing technology, metabolite quantification methods, and widespread use of cytometry-based immunophenotyping, will continue to improve the feasibility of these techniques as diagnostic tools. Better understanding of the relationships and dependencies between the immunologic, metabolic, and genetic perturbations seen in AML can allow for refined usage of available and emerging therapeutics and combinations thereof.