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. 2019 Nov 8;10:1391. doi: 10.3389/fphys.2019.01391

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Copyright © 2019 Altamirano-Diaz, Kassay, Serajelahi, McIntyre, Filler and Kharche.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Major factors inducing hypertension. Left column shows data for aortic systolic pressure, sys. P_SAT. Right column shows data for the aorta’s systolic blood flow, sys. Q_SAT. Top row (Ai,Aii) shows data for effects of augmented peripheral resistance, middle row (Bi,Bii) shows data for effects of augmented arterial stiffnesses, and bottom row (Ci,Cii) shows data for heart rate. In panels (Ai,Aii), baseline conditions are indicated by “c”. In panels (Ai) through (Bii), “h1” indicates hypertension 1, and “h2” indicates hypertension 2. The third circle indicates the baseline conditions. The heart rate period under hypertension (both h1 and h2) is shown as an “x” in panels (Ci,Cii).