Figure 4.

Results from Analyses of Individualized Microbiome Models

(A) Depiction of microbial sulfur metabolism and generation of methionine from aspartate. The bold red arrow indicates the suggested increased overall flux toward final products.

(B) Results of the statistical analyses of reaction abundances from fractional regressions.

(C) Boxplots in PDs and controls for altered secretion potentials in the pathway depicted above.

(D) Boxplots in PDs and controls for the abundance of Bilophila wadsworthia. Reaction abbreviations correspond to those in www.vmh.life.