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Characteristics of three genes methylation between HBV-positive carcinoma serums and HBV-negative carcinoma serums in HCC
| Gene | Studies (n) |
Overall OR (95% CI) |
I2 | P value |
HBV-positive carcinoma serums/HBV-negative carcinoma serums |
|---|---|---|---|---|---|
| p16 | 10 | 2.51 [1.16, 5.44] | 55% | 0.02 | 460/122 |
| RASSF1A | 7 | 1.30 [0.76, 2.23] | 0% | 0.34 | 371/69 |
| APC | 3 | 5.11 [2.09, 12.52] | 0% | 0.0004 | 228/46 |
