. 2019 Oct 15;10(25):6207–6216. doi: 10.7150/jca.37335

Table 1.

Association of the Expression of p53, PCDH17, and Beclin-1 With Clinicopathologic Characteristics and Survival Estimates of 75 Bladder Cancer Patients Who Underwent Surgical Treatment.

Characteristic	Patients		p53 Mutation				p53 Expression				PCDH17 Expression				Beclin-1 Expression
	No.	%	Mutation		Pearson Correlation	p-value	High-expression		Pearson Correlation	p-value	Low-expression		Pearson Correlation	p-value	Low-expression		Pearson Correlation	p-value
	No.	%	No.	%	Pearson Correlation	p-value	No.	%	Pearson Correlation	p-value	No.	%	Pearson Correlation	p-value	No.	%	Pearson Correlation	p-value
Total	75	100	50	66.7			49	65.3			48	64.0			57	76.0
Gender					0.115	0.319			-0.037	0.746			-0.016	0.888			-0.165	0.154
Female	16	21.3	9	56.3			11	68.8			10	62.5			10	62.5
Male	59	78.7	41	69.5			38	64.4			38	64.4			47	79.7
Smoking					-0.019	0.867			0.003	0.979			-0.025	0.828			-0190	0.100
Yes	29	38.7	19	65.5			19	65.5			19	65.5			25	86.2
No	46	61.3	31	60.9			30	65.2			29	63.0			32	69.6
Alcohol					-0.108	0.348			-0.027	0.818			-0.054	0.642			-0.040	0.728
Yes	19	25.3	11	57.9			12	63.2			13	68.4			15	78.9
No	56	74.7	39	69.6			37	66.1			35	62.5			42	75.0
Diabetes					0.087	0.451			0.097	0.403			-0.021	0.859			-0.111	0.334
Yes	9	12.0	7	77.8			7	77.8			6	66.7			8	88.9
No	66	88.0	43	65.2			42	63.6			42	63.6			49	74.2
BMI					-0.097	0.399			-0.017	0.883			0.110	0.340			0.147	0.203
<24	47	62.7	33	70.2			31	66.0			32	68.1			38	80.9
>=24	28	37.3	17	60.7			18	64.3			16	57.1			19	67.9
Tumor stage					0.354	0.002^**			0.224	0.052			-0.236	0.041^*			-0.203	0.079
Ta, Tis, T1	60	80.0	35	58.3			36	60.0			35	58.3			43	71.7
T2, T3, T4	15	20.0	15	100			13	86.7			13	86.7			14	93.3
Invasiveness					0.354	0.002^**			0.224	0.052			-0.236	0.041^*			-0.203	0.079
Invasive	15	20.0	15	100			13	86.7			13	58.3			14	93.3
Non-Invasive	60	80.0	35	58.3			36	60.0			35	86.7			43	71.7
p53 Mutation									0.614	<0.001^**			-0.471	<0.001^**			-0.530	<0.001^**
Wide type	25	33.3					6	24.0			8	32.0			11	44.0
Mutation	50	66.7					43	86.0			40	80.0			46	92.0
p53 expression					0.614	<0.001^**							-0.212	0.066			-0.247	0.033^*
Low	26	34.7	7	26.9							13	50.0			16	61.5
High	49	65.3	43	87.8							35	71.4			41	83.7
PCDH17 expression					-0.471	<0.001^**			-0.212	0.066							0.359	0.002^**
Low	48	64.0	40	83.3			35	72.9							42	87.5
High	27	36.0	10	37.0			14	51.9							15	55.6
Beclin-1 expression					-0.530	<0.001^**			-0.247	0.002^**			0.359	0.002^**
Low	57	76.0	46	80.7			41	71.9			42	64.0
High	18	24.0	4	22.2			8	44.4			6	33.3

*p-value<0.05; ** p-value<0.01