Table 3.
KEGG pathway analysis of differentially expressed genes in the ccRCC
| Category | Term | Count | Generatio (%) | PValue |
|---|---|---|---|---|
| Up-regulated DEGs | hsa04510:Focal adhesion | 26 | 7.49 | 1.05E-10 |
| hsa04145:Phagosome | 21 | 6.05 | 2.41E-09 | |
| hsa04512:ECM-receptor interaction | 16 | 4.61 | 5.74E-09 | |
| hsa05146:Amoebiasis | 16 | 4.61 | 9.13E-08 | |
| hsa05416:Viral myocarditis | 12 | 3.45 | 2.01E-07 | |
| Down-regulated DEGs | hsa00010:Glycolysis / Gluconeogenesis | 6 | 3.48 | 0.001069 |
| hsa00350:Tyrosine metabolism | 4 | 2.32 | 0.007754 | |
| hsa01100:Metabolic pathways | 23 | 13.37 | 0.022939 | |
| hsa04922:Glucagon signaling pathway | 5 | 2.90 | 0.028494 | |
| hsa00640:Propanoate metabolism | 3 | 1.74 | 0.04214 |