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. 2019 Sep 2;144(3):e20190178. doi: 10.1542/peds.2019-0178

TABLE 2.

Treatment Response of Participants in the PRT-P Group or DTG

Mean (SD) Group × Time Interaction Cohen’s d (Week 24)
Baseline Week 24 F P
PRT-P Group (n = 23) DTG (n = 20) PRT-P Group (n = 23) DTG (n = 20)
SLO
 Total utterances 49.9 (30.7) 52.8 (23.9) 71.3 (27.3) 53.4 (28.8) 5.808 .026 0.64
BOSCC
 Total score 34.3 (7.5) 34.6 (4.2) 26.5 (6.2) 34.4 (4.9) 28.794 <.001 1.41
 Social communication subscore 23.8 (4.3) 25.1 (4.0) 18.3 (4.8) 24.63 (3.9) 9.562 .004 1.45
CDI
 Words produced out of 396 118.2 (110.9) 54.2 (72.3) 194.9 (133.7) 84.4 (93.5) 5.663 .022 0.96
 Words produced out of 680 141.9 (129.9) 80.2 (105.7) 256.6 (200.1) 112.9 (148.1) 6.039 .018 0.82
Vineland-II
 Expressive v-scale score 7.23 (1.9) 6.7 (1.3) 7.6 (2.4) 6.2 (1.6) 3.587 .066 0.58
 Communication standard score 63.8 (14.8) 62.5 (11.6) 64.9 (16.8) 62.6 (13.9) 0.230 .634 0.15
PLS-5
 Expressive standard score 58.4 (8.9) 57.9 (7.9) 58.7 (10.2) 56.9 (10.5) 0.384 .539 0.17
MSEL
 MSEL expressive language raw score 18.2 (7.3) 14.9 (7.6) 21.0 (8.7) 17.3 (6.9) 0.082 .775 0.47
 MSEL composite score 49.9 (1.8) 50.9 (5.7) 51.1 (3.9) 53.8 (10.1) 0.425 .519 0.35
SRS-2
 Social communication raw score 95.8 (26.4) 98.3 (25.6) 91.9 (22.8) 93.1 (27.4) 0.061 .806 0.05
CGI
 CGI-S 5.4 (0.5) 5.4 (0.6) 5.13 (0.7) 5.40 (0.5) 5.914 .019 0.44
 CGI-I 2.6 (0.8) 3.4 (0.7) 6.858 <.001 1.06

CDI: df (1, 40), controlling for baseline difference; CDI 396: df (1, 39), F = 4.459, P = .041; CDI 680: df (1, 39), F = 4.134, P = .049; Vineland-II: df (1; 39); PLS-5: df (1, 41); MSEL: df (1, 41); CGI: df (1, 41), focused on social and communication symptoms. df, degrees of freedom; —, not applicable.