Figure 1.
IL-6 expression is correlated with inferior prognosis in patients with osteosarcoma. (A)Statistical analysis of IL-6 expression levels in osteosarcoma and adjacent non-tumor tissue specimens. (B) Association of IL-6 serum expression with clinicopathological traits in patients with osteosarcoma. (C) Plasma IL-6 levels were significantly higher in patients with tumor, node, metastasis (TNM) stage III-IV osteosarcoma than in those with stage I-II disease; (D) Plasma IL-6 levels were significantly higher in patients with lung metastasis than in those with no lung metastasis.