Figure 1.

A: Detailed method of evaluating metastatic brain tumors; The maximum diameter (a) of the tumor (TS) was measured in T1-weighted Gd-enhanced image. Then we also measured the maximum diameter of its associated peritumoral brain edema (PTBE) (b) at the same slice of the T2-weighted image. The “peritumoral brain edema index” (PBEI) was defined as (b-a)/a. B: T1-weighted Gd-enhanced image demonstrates the patient with diffuse brain metastases. C: Two patients with hippocampus and Peri-Hippocampus region metastases in SBM group. The red circle means the hippocampus area, the blue circle means the Peri-Hippocampus region.