Table 1.
Patient characteristics
| Baseline characteristic | MSC sample population (n = 70) | Not in MSC sample population (n = 585) | P* |
|---|---|---|---|
| Age, median (range) | 43.0 (22-65) | 46.0 (23-65) | .068† |
| Sex | |||
| Male | 48 (68.6) | 310 (53.0) | .013 |
| Female | 22 (31.4) | 275 (47.0) | |
| Baseline WBC, median (range) | 11.0 (0.8-583.1) | 7.9 (0.11-889.6) | .24† |
| PH status | |||
| PH− | 51 (73.9) | 392 (68.7) | .37 |
| PH+ | 18 (26.1) | 179 (31.3) | |
| Missing/failed | 1 | 14 | |
| T(4,11) | |||
| Absent | 62 (91.2) | 497 (92.4) | .33 |
| Present | 6 (8.8) | 41 (7.6) | |
| Missing/failed | 2 | 47 | |
| Complexity | |||
| Absent | 53 (96.4) | 425 (95.1) | .97‡ |
| Present | 2 (3.6) | 22 (4.9) | |
| Missing/failed | 15 | 138 | |
| HoTr/near-haploidy | |||
| Absent | 55 (96.5) | 409 (89.7) | .10 |
| Present | 2 (3.5) | 47 (10.3) | |
| Missing/failed | 13 | 129 | |
| Any cytogenetic risk factors | |||
| Absent | 28 (50.0) | 186 (39.6) | .13 |
| Present | 28 (50.0) | 284 (60.4) | |
| Missing/failed | 14 | 115 | |
| High-risk baseline | |||
| Standard risk | 13 (19.4) | 64 (11.5) | .064 |
| High risk | 54 (80.6) | 492 (88.5) | |
| Unknown, assumed standard | 13 (19.4) | 64 (11.5) | .064 |
Data are expressed as n (%), unless otherwise stated.
HoTr, low hypodiploid/near triploidy; PH, Philadelphia chromosome; t4;11, presence of KMT2A/AFF1 rearrangement; WBC, white blood cell.
*
χ2, unless otherwise stated.
†
Wilcoxon Mann-Whitney test.
‡
Fisher’s exact test.