Table 1.

Biophysical properties of WT and V810M channels.

	Current density		Activation (mV)			Steady-state fast inactivation (mV)			Steady-state slow inactivation (mV)			Deactivation (ms)
Nav1.7	pA/pF	n	V1/2	k	n	V1/2	k	n	V1/2	k	n	–40 mV	n
WT	380.1 ± 42.2	18	–18.5 ± 0.7	7.7 ± 0.1	18	–83.7 ± 1.4	6.7 ± 0.2	18	–72.2 ± 1.7	14.0 ± 0.6	8	0.26 ± 0.01	17
V810M	577.6 ± 80.3*	16	–21.5 ± 1.2*	7.4 ± 0.3	16	–85.5 ± 1.2	6.7 ± 0.2	17	–69.8 ± 1.7	14.5 ± 0.6	7	0.32 ± 0.01**	11

*p < 0.05, **p < 0.0001 significantly different from WT; n represents the number of cells from which recordings were acquired.