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. 2019 Sep 27;134(20):1764–1775. doi: 10.1182/blood.2019001736

Figure 5.

Figure 5.

VEGFD is not required for lymphangiogenesis in the mouse hemostatic tail injury model. (A) Schematic of tail injury in control (Vegfd+/0 and Vegfd+/−) and Vegfd KO (Vegfd−/0 and Vegfd−/−) mice. (B) Representative images of tail lymphangiograms across the injury site on day 15 after tail injury in control and Vegfd KO animals. Yellow arrows indicate restored lymph flow across the injury site. (C) Healing curves for restoration of lymphatic flow in control and Vegfd KO animals. (D) Healing curves for restoration of lymphatic flow in Vegfc cKO and Vegfc cKO;Vegfd KO animals. Note that VEGFD is not required even in the absence of VEGFC. Scale bars = 500 µm. ns, not significant.