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. 2019 Oct 21;9(26):8253–8265. doi: 10.7150/thno.37351

Figure 3.

Figure 3

Mesenchymal stem cell (MSC) transplantation attenuates SS-like diseases in NOD mice. (A) Representative images of H&E staining of salivary glands in PBS (A) and MSC treated NOD mice. Yellow arrows indicate infiltrating lymphocytes. (B) Lymphocyte infiltrations in salivary glands of mice were evaluated for histological scores. (C) Salivary flow rates in PBS (n=5) (12-week old) and MSC treatment NOD mice (n=5) (12-week old). (D)Serum IL-27 was compared between PBS (n=5) (12-week old) and MSC treatment groups (n=5) (12-week old). (E-H) Representative FACS analysis of Treg and Th17 cells of spleens (E, F) and cervical lymph nodes (G, H)(n=5). Data were based on three independent experiments. Data are presented as mean±SEM. *,p<0.05, **, p<0.01.