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. 2019 Oct 21;9(26):8253–8265. doi: 10.7150/thno.37351

Figure 4.

Figure 4

IL-27 modulates the proliferation and differentiation of Th17 and Treg cells in PBMCs and naïve CD4+ T cells. (A, B) Treg and Th17 cells in human PBMCs with and without IL-27 treatment. (A) Fluorescence staining of CD4, Foxp-3 and IL-17 in human PBMCs. (B) Summary of the frequencies of Treg and Th17 cells (n=5). (C, D) Flow cytometric analysis of Treg and Th17 cells, which were differentiated from mouse naïve CD4+ T cells in the presence or absence of IL-27 (n=5). Data are presented as mean±SEM. Data were based on three independent experiments. *, p<0.05.