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. 2019 Nov 8;10:771. doi: 10.3389/fendo.2019.00771

Table 5.

Clinical characteristics, hormonal levels, and oxidative stress parameters of the CAT C-262T genotypes in PCOS patients and controls.

Controls PCOS
CC CT+TT CC CT+TT
(n = 499) (n = 35+1) (n = 614) (n = 38+2)
Age (years) 28.20 ± 4.07 27.44 ± 5.15 25.05 ± 4.24 24.33 ± 3.70
BMI (kg/m2) 21.14 ± 2.88 20.84 ± 2.59 23.25 ± 4.26 22.97 ± 4.40
Waist circumference (cm) 73.82 ± 8.37 71.46 ± 8.34 80.10 ± 11.44 78.41 ± 11.28
Waist-to-hip ratio 0.82 ± 0.06 0.80 ± 0.06 0.85 ± 0.07 0.84 ± 0.07
F-G score 0.24 ± 0.67 0.47 ± 1.32 1.73 ± 2.06 1.93 ± 2.14
Acne grade score 0.15 ± 0.37 0.00 ± 0.00a 0.64 ± 0.90 0.83 ± 0.96
SBP (mmHg) 113.07 ± 11.48 110.79 ± 11.50 114.82 ± 10.72 115.26 ± 10.69
DBP (mmHg) 73.73 ± 8.71 73.55 ± 8.00 75.68 ± 8.83 77.44 ± 10.41
AOV (ml) 7.58 ± 2.72 8.27 ± 4.39 10.05 ± 3.96 11.13 ± 5.82
Hormonal levels
TT (nmol/L) 1.50 ± 0.53 1.66 ± 0.53 2.35 ± 0.78 2.36 ± 0.74
SHBG (nmol/L) 54.61 ± 27.57 54.37 ± 20.03 34.81 ± 27.07 40.07 ± 22.67
FAI 3.42 ± 2.15 3.14 ± 1.51 9.89 ± 7.08 7.99 ± 6.76
LH/FSH 1.27 ± 1.27 1.10 ± 0.81 2.31 ± 1.30 2.11 ± 0.91
Oxidative stress parameters
TOS (nmol H2O2 Equiv./mL) 11.17 ± 5.30 12.14 ± 5.49 14.85 ± 10.65 16.16 ± 12.56
T-AOC (U/ml/min) 14.54 ± 2.75 13.97 ± 1.77 15.77 ± 3.09 16.13 ± 2.62
OSI 0.80 ± 0.41 0.88 ± 0.37 0.99 ± 0.80 1.00 ± 0.69
MDA (nmol/ml) 3.66 ± 1.08 3.64 ± 1.02 4.35 ± 1.28 4.21 ± 1.76

Values are presented as the mean ± SD.

AOV, average ovarian volume; BMI, body mass index; DBP, diastolic blood pressure; FAI, free androgen index; F-G score, Ferriman–Gallwey score; FSH, follicle-stimulating hormone; LH, luteinizing hormone; MDA, malondialdehyde; OSI, oxidative stress index; SBP, systolic blood pressure; SHBG, sex hormone-binding globulin; T-AOC, total antioxidant capacity; TOS, total oxidant status; TT, total testosterone.

Comparisons of all parameters were corrected for differences in age and BMI between the 2 subgroups except the parameters of age and BMI.

a

P < 0.05, compared with the CC genotype subgroup in controls.