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. Author manuscript; available in PMC: 2019 Nov 15.
Published in final edited form as: Nature. 2017 Mar 1;543(7644):199–204. doi: 10.1038/nature21374

Extended Data Figure 4 |. Heterogeneity among lncRNA gene categories.

Extended Data Figure 4 |

a, Epigenomic features surrounding TSS. The y axis refers to the fraction of TIR overlaps with peaks of the corresponding epigenomic signal from the Roadmap Epigenome Consortium23. b, Genomic features surrounding TSS. Sequence features conducive to generating longer transcripts are enrichment of 5′ splice site (5′ SS) and depletion of polyadenylation sites (PAS). Sequence features associated with transcription initiation include CpG islands, INR (initiator) motif and TATA box motif. c, Core promoter motifs. Grey dashed lines indicate whole-genome background.