Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Nov 14;17:375. doi: 10.1186/s12967-019-2128-4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 5 — tolDC inhibit bystander NK-cell proliferation. Cell proliferation dye (CFSE/CTV)-labelled PBMC of IA patients were cultured with an HSP-peptide pool (HSP60p1, HSP60p2 and B29; 4 μg/ml per peptide) (a, b) or CA (1:1000) (c, d) and tolDC (tolDC) or without moDC (−) for 9 days. a–d Percentages of CFSE/CTV⁻ life NK-cells were measured using flow cytometry. Gating strategy (a) HSP-peptide graph (b) and CA graphs (c, d) are shown. (d) TGF-βRI (ALK5) inhibitor (SB-505124) was added at 1 µM. (N = 2). Ratios were measured by dividing the percentage of CFSE/CTV⁻ NK-cells of tolDC cultures by the percentage of CFSE/CTV⁻ NK-cells of non-moDC cultures. Two-tailed paired Student T-test was used. ***p ≤ 0.001