Fig. 1.

Resource consumption. a Aligner. b SV caller. The computing time (Wall Time), maximum memory usage (Max Memory), and file system operations (FS Operations) are shown. LAST’s Wall Time included Picky’s representative read selection step because Picky requires a specific output format from LAST in place of the default output. SV callers are noted with respect to the aligner used to map the reads. The CHM13 dataset was analyzed under multiple cluster configurations and therefore was not included in the computational resource evaluation