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. 2019 Nov 15;17:94. doi: 10.1186/s12958-019-0526-3

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Building a euthyroid HT mouse model on Day E4.5. a Representative macroscopic images of thyroid glands from Con mice and HT mice. b Histology of the thyroid detected by HE staining at magnification × 200. Arrow: thyroid follicle; Arrowhead: infiltrated monocytes. c-e Levels of thyroiditis-related parameters. c Quantitation of the degree of monocyte infiltration in thyroids (Mann-Whitney test), d Serum anti-Tg, e Serum anti-TPO. f-h Serum levels of thyroid function-related parameters. f FT3, g FT4, h TSH. Data are presented as the mean ± SEM, n = 28; ns, not significant; ^***p < 0.001, vs. Con