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. 2019 Nov 14;20:239. doi: 10.1186/s13059-019-1856-3

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — ABCA7 VNTR length estimates. TR length estimates (the number of TR units is depicted on the y-axis) per positive strand (red) or negative strand (blue) PromethION sequencing reads (dots) are shown in comparison to the Southern blotting lengths (dashed lines). a Comparison of the five methods (Albacore + tandem-genotypes (tg), Scrappie (S.) events + tg, S. raw + tg, Guppy “flip-flop” + tg, and NanoSatellite) for NA19240, the individual with most sequencing reads. b Comparison of the five methods for Subject05, the individual with the largest expanded ABCA7 VNTR allele. c NanoSatellite ABCA7 VNTR length estimations for all individuals