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. 2019 Nov 14;19:1108. doi: 10.1186/s12885-019-6328-3

Table 3.

Univariate analyses for PFS and OS among 127 patients who underwent curative surgery for IHCC

Median survival

(month)

P value

Median survival

(month)

P value
Age
  < 55 years old 10.0 18.6
  ≥ 55 years old 18.5 0.046 34.8 0.002
Sex
 Male 15.6 28.8
 Female 10.5 0.778 21.0 0.599
TMN staging
 I and II 30.2 45.5
 III and IV 7.7 < 0.001 15.7 < 0.001
T classification
 I 15.4 23.5
 II 10.4 40.2
 III 16.2 24.2
 IV 4.0 0.061 Not reached 0.948
Lymph node metastasis
 N0 21.2 40.2
 N1 6.1 < 0.001 11.5 < 0.001
Tumor differentiation
 Well 51.7 Not reached
 Moderate 15.6 28.8
 Poor 6.7 0.003 19.4 0.027
Resection Margin
 Positive 4.8 21.0
 Negative 15.6 0.020 25.2 0.304
Tumor size
  < 5 cm 19.8 28.8
  ≥ 5 cm 6.7 0.001 21.5 0.071
Hepatitis
  Positive 10.4 19.0
 Negative 17.6 0.005 25.2 0.079
Hypertension
 Yes 11.7 21.1
 No 15.6 0.856 43.0 0.074
Bile duct stone
 Yes 11.7 18.6
 No 15.6 0.657 30.4 0.063
Jaundice
 Yes 10.2 19.4
 No 15.4 0.406 25.2 0.386
Fever
 Yes 10.5 21.1
 No 15.4 0.737 24.8 0.920
Postoperative chemotherapy
 Yes 11.7 43.0
 No 15.6 0.939 23.5 0.170
CA-199
 Elevated 15.4 26.0
 Not elevated 11.7 0.961 28.8 0.887
CEA
 Elevated 7.7 15.5
 Not elevated 17.6 0.183 40.2 0.016