Fig. 4.

Classification of large-scale rearrangements. a Total count of large-scale rearrangements in three sequenced genomes per cell line, classified by CREST as interchromosomal translocation (CTX), intrachromosomal translocation (ITX), deletion, or insertion. b The size distribution of large deletions. c Reconstitution of the rearrangement profile of cell lines with > 10 events using 6 rearrangement signatures (Rsig). d Classification of rearrangements in the same cell lines according to categories used for the definition of rearrangement signatures [12]. Rearrangement signature 5 is shown for comparison