Table 2.
Changes in number of daily bowel movements in past seven days over 8 weeks study period
| Visit time | Mebeverine group (n=20) | Placebo group (n=20) | p | |
|---|---|---|---|---|
| Screening | Range | 4.0 - 12.00 | 4.0 - 10.00 | 0.617 |
| Mean±SD | 5.6±2.06 | 5.6±1.53 | ||
| Median (IQR) | 5.0 (4.0 - 6.0) | 5.0 (4.0 - 6.0) | ||
| End of 4 weeks | Range | 2.0 - 12.0 | 2.0 - 8.0 | 0.766 |
| Mean±SD | 4.3±2.18 | 4.2±1.30 | ||
| Median (IQR) | 4.0 (3.0 - 5.0) | 4.0 (3.5 - 4.0) | ||
| End of 8 weeks | Range | 2.0 - 12.0 | 2.0 - 8.0 | 0.756 |
| Mean±SD | 3.9±2.34 | 3.8±1.51 | ||
| Median (IQR) | 3.5 (2.0 - 4.5) | 4.0 (3.0 - 4.0) | ||
| Within group P | < 0.001 | < 0.001 |
Abbreviations: IQR=interquartile range; SD=standard deviation. p value in the last column is for intergroup comparison by Mann-Whitney t test. The P value for within group comparison is from Friedman’s analysis of variance