Table 3.
Most Significant Canonical Pathways
| Pathway | p | Overlapa | |
|---|---|---|---|
| 1 | EIF2 signaling | 6.89E-25 | 19.4% (45/232) |
| 2 | Complement system | 9.80E-16 | 43.2% (16/37) |
| 3 | Regulation of eIF4 and p70S6K signaling | 4.52E-15 | 17.3% (29/168) |
| 4 | Acute-phase response signaling | 2.51E-14 | 16.2% (29/179) |
| 5 | mTOR signaling | 1.07E-12 | 13.6% (30/221) |
Number of proteins detected in our samples out of the total number of proteins included in the pathway by the Ingenuity pathway analysis.