Table 1.
Accession ID* | Description | Protein Function | Fitness score^ | Report on experimental myristoylation |
---|---|---|---|---|
TGME49_207460 | Rab 5b | Intracellular membrane trafficking | −1.35 | (Ebine, et al., 2016) Ψ |
TGME49_223940 | GAP45 | Gliding motility | −4.14 | (Frenal, et al., 2010) |
TGME49_237820 | ISP2 | Parasite division | −2.04 | (Beck, et al., 2010) |
TGME49_245710 | phosphatidylinositol-4-phosphate 5-kinase, putative | Calcium signaling | 1.15 | (Wright, et al., 2015) # |
TGME49_249970 | acylated pleckstrin-homology domain-containing protein (APH) | Microneme exocytosis | −5.53 | (Bullen, et al., 2016) |
TGME49_260820 | ISP1 | Parasite division | −2.04 | (Beck, et al., 2010) |
TGME49_262860 | ADP-ribosylation factor family protein 1, putative | Dense granule proteins release | −0.52 | (Wright, et al., 2015)# |
TGME49_268960 | 5’-AMP-activated protein kinase subunit beta-1 family protein, putative | Energy sensor | −3.95 | (Wright, et al., 2016, Wright, et al., 2015) #,& |
TGME49_269780 | ADP-ribosylation factor, putative | Vesicle biogenesis 32 | −1.28 | (Wright, et al., 2015) # |
TGME49_281580 | PP2C-like, putative | Protein phosphatase | −1.06 | (Wright, et al., 2016, Wright, et al., 2015) #,& |
TGME49_305860 | CDPK3 | Parasite egress | −0.09 | (Garrison, et al., 2012) |
TGME49_316540 | ISP3 | Parasite division | −0.63 | (Beck, et al., 2010) |
Toxodb release 40 (15 Oct 2018).
Data represent mean CRISPR phenotype scores reported by Sidik et al. (Sidik, et al., 2016)
Reported to be myristoylated in L. donovani
Reported to be myristoylated in P. falciparum
Reported to be myristoylated in T. brucei