Fig. 5. Controlled delivery of DOX into HeLa cells by H3-PC4AP-DOX (36). (A) Fluorescence confocal microscopy analyses showing the cellular location of DOX after treatment of HeLa cells with DOX and 36. The images were obtained by overlaying the DAPI channel (excitation at 408 nm and emission at 425–475 nm), the DOX channel (excitation at 561 nm and emission at 570–620 nm), and the DIC channel. (B) Light-dependence of 36 cytotoxicity to HeLa cells.
