Table 3. Hepatic mRNA levels of markers of inflammation and stress of the endoplasmic reticulum (ER) before and 12 hours after lipopolysaccharide (LPS) challenge in horses and ponies fed placebo or green tea and curcuma extract (GCE).
Values are presented as median (25./75. percentiles). Different superscript letters indicate significant differences (P < 0.05) within a row.
| Parameter | Placebo | GCE | ||
|---|---|---|---|---|
| Before LPS | 12 h after LPS | Before LPS | 12 h after LPS | |
| TNF-α | 7.66a (2.98/10.3) | 4.37a (3.94/9.68) | 4.32a (3.12/6.2) | 7.88a (3.86/12) |
| Haptoglobin | 1.03a (0.87/1.33) | 1.35b (1.24/1.49) | 1.18ab (0.64/1.7) | 1.51ab (1.15/1.7) |
| NF-κB | 2.21a (1.18/3.76) | 2.12a (1.63/3.32) | 2.04a (1.59/2.87) | 3.70a (2.22/4.63) |
| ATF4 | 1.87a (0.96/3.24) | 1.38a (1.06/1.58) | 1.72a (1.23/2.77) | 1.19a (0.51/1.87) |
| CD68 | 4.58a (2.8/9.45) | 8.63b (6.02/11.8) | 5.49ab (3.65/6.65) | 11.58b (6.96/16) |
| FGF21 | 1.46ab (0.12/5.18) | 0.15b (0.05/0.59) | 1.65a (0.14/6.36) | 0.08ab (0.02/1.6) |
| IL-6 | 7.71a (3.64/74.9) | 4.29a (2.05/8.22) | 1.81a (1.7/3.78) | 3.55a (2.35/9.08) |
| IL-1β | 8.63ab (6.91/16.6) | 26.93b (5.79/34.9) | 13.19ab (10.13/15.1) | 10.53a (9.14/24.9) |