. Author manuscript; available in PMC: 2020 Sep 1.

Published in final edited form as: Mayo Clin Proc. 2019 Aug 15;94(9):1731–1742. doi: 10.1016/j.mayocp.2019.02.028

Table 2. Severe hypoglycemia-related events within two years.

The number of severe hypoglycemia hospitalizations and emergency department visits was estimated by applying rates from McCoy et al 2016¹⁴ to non-pregnant NHANES participants with diabetes who met analogous inclusion criteria (≥18 years and HbA_1c <7.0%). Events attributable to intensive treatment were calculated by applying event rates expected with non-intensive treatment to those patients receiving intensive therapy. 95% confidence intervals (CI) were estimated using probabilistic sensitivity analysis (PSA).

	Non-intensive treatment	Intensive treatment	Total	Events Attributable to Intensive Treatment
Hospitalizations
Low complexity	8,127	3,654	11,781	787 (95% CI, 0 - 1,812)
High complexity	10,406	9,324	19,730	3987 (95% CI, 374 - 8,925)
U.S. total	18,533	12,978	31,511	4,774 (95% CI, 945 - 9,714)
Emergency department visits
Low complexity	2,902	2,436	5,338	525 (95% CI, 0 - 1,241)
High complexity	15,610	10,006	25,616	4,279 (95% CI, 431 - 9,286)
U.S. total	18,512	12,442	30,954	4,804 (95% CI, 862 - 9,851)