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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: Leuk Res. 2019 Jul 3;84:106180. doi: 10.1016/j.leukres.2019.106180

Figure 1. Leukemia cells activate resting ECs resulting in altered leukemia cell proliferation.

Figure 1.

(A) Representative flow cytometry plots showing E-selectin levels on KG-1 activated HUVECs and non-activated HUVEC controls. (B) The levels of E-selectin expression on the surface of ECs showed significant increases when activated with KG-1 cells in co-culture. * p < 0.05 (C) Representative flow cytometry plots showing BrdU uptake by adherent and non-adherent AML cells in contact co-cultures of HUVECs and KG-1 cells. (D) BrdU uptake in non-adherent KG-1 cell populations was significantly higher in comparison to adherent populations indicating a proliferative phenotype. * p < 0.05