Table 3.
Number of cases in Mendelian-randomization analysis
| Outcomes | N totala | N, EMRb | N, SRc | N, bothd |
|---|---|---|---|---|
| SBPe | 319 778 | NA | NA | NA |
| DBPe | 319 779 | NA | NA | NA |
| Hypertension | 106 405 | 16 905 (15.9%) | 42 317 (39.8%) | 47 183 (44.3%) |
| T2D | 15 958 | 13 692 (85.8%) | 671 (4.2%) | 1595 (10.0%) |
| IHD | 28 337 | 13 062 (46.1%) | 2556 (9.0%) | 12 719 (44.9%) |
| BMIe | 338 172 | NA | NA | NA |
| Depression | 23 294 | 5382 (23.1%) | 13 628 (58.5%) | 4284 (18.4%) |
| Non-vertebral fracture | 23 603 | 15 811 (67.0%) | 6382 (27.0%) | 1410 (6.0%) |
| All-cause mortality | 9830 | 9830 (100%) | NA | NA |
EMR, electronic medical records; SR, self-reported medical conditions; SBP, systolic blood pressure; DBP, diastolic blood pressure; T2D, type 2 diabetes; IHD, ischaemic heart disease; BMI, body mass index.
a
Total number of cases.
b
Number of cases captured by EMR data only.
c
Number of cases captured by SR data only.
d
Number of cases captured by both EMR and SR.
e
Continuous variable, data come from baseline anthropometric measurement data.