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. 2019 Nov 15;25:756–765.

Table 2. Summary of chemokine in the measured vitreous.

Chemokine (pg/ml) Control (n=20)
 RVO (n=25)
 p Value
Median IQR Median IQR
CCL21
 116.26
 41.31
 203.43
 56.44
 <0.001*
CXCL13
 0.41
 0.15
 0.65
 0.2
 <0.001*
CCL27
 1.37
 0.51
 4.1
 1.25
 <0.001*
CXCL5
 162.54
 31.5
 150.32
 27.03
 0.144
CCL11
 1.78
 0.52
 2.12
 0.6
 0.073
CCL24
 3.89
 0.71
 5.67
 0.97
 <0.001*
CCL26
 1.23
 0.11
 1.36
 0.3
 0.064
CX3CL1
 5.91
 1.95
 8.43
 1.46
 <0.001*
CXCL6
 0.24
 0.56
 0.86
 0.15
 0.001*
GM-CSF
 4.2
 1.23
 3.99
 1.06
 0.335
CXCL1
 6.31
 3.58
 8.12
 2.85
 0.096
CXCL2
 7.95
 1.17
 8.23
 1.54
 0.138
CCL1
 4.42
 0.75
 5.08
 0.74
 0.07
IFN-γ
 1.42
 0.51
 2.03
 0.26
 <0.001*
IL-1β
 0.26
 0.07
 0.37
 0.06
 <0.001*
IL-2
 0.53
 0.01
 0.73
 0.04
 <0.001*
IL-4
 0.88
 0.74
 2.76
 0.73
 <0.001*
IL-6
 2.89
 7.65
 9.13
 0.84
 0.038*
IL-8
 1.35
 1.22
 8.93
 7.09
 <0.001*
IL-10
 0.83
 0.23
 2.14
 0.71
 <0.001*
IL-16
 11.24
 2.21
 31.03
 21.83
 <0.001*
CXCL10
 9.78
 11.42
 63.35
 13.37
 <0.001*
CXCL11
 0.11
 0.04
 0.17
 0.04
 <0.001*
CCL2
 73.24
 36.6
 72.56
 25.68
 0.411
CCL8
 0.23
 0.21
 0.94
 0.09
 <0.001*
CCL7
 7.95
 1.49
 10.19
 0.4
 <0.001*
CCL13
 0.2
 0.04
 0.33
 0.07
 <0.001*
CCL22
 3.51
 0.79
 6.15
 0.32
 <0.001*
MIF
 146.2
 177.09
 513.21
 27.28
 <0.001*
CXCL9
 7.02
 9.98
 54.32
 19.78
 <0.001*
CCL3
 0.76
 0.53
 1.41
 0.29
 <0.001*
CCL15
 55.1
 40.98
 101.12
 6.38
 <0.001*
CCL20
 0.37
 0.14
 0.65
 0.11
 <0.001*
CCL19
 2.78
 2.05
 16.12
 1.39
 <0.001*
CCL23
 1.94
 0.66
 3.51
 0.61
 <0.001*
CXCL16
 82.11
 17.04
 87.54
 13.14
 0.936
CXCL12
 44.89
 17.09
 52.34
 20.39
 0.178
CCL25
 7.44
 2.67
 14.21
 1.23
 <0.001*
TNF-α 1.03 0.98 6.87 1.78 <0.001*

RVO=retinal vein occlusion; IQR=interquantile range; CCL=C-C motif ligand;CXCL=C-X-C motif ligand; GM-CSF=granulocyte macrophage colony-stimulating factor ; IFN-γ=interferon-gamma ; IL=Interleukin; MIF=macrophage migration inhibitory factor; TNF-α=tumor necrosis factor-alpha; *=Statistical significant p value by Mann–Whitney U test