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Cytokine levels (IL‐1β, IL‐1α, IL‐18, TNF‐α, IL‐6 and IL‐1Ra) in the supernatant of polarized monocytes (M1: proinflammatory phenotype, M2: anti‐inflammatory phenotype, M0: basal conditions) of Proband I, patients out of crisis (n = 6), and Proband II as compared with apparently healthy donors (n = 4) in the presence or absence of LPS.
