Table 1.

Clinical diagnosis and crisis features of NLRP3‐AID members of Family I and Family II

	Family I										Family II
	Proband I (III.3)	II.I	II.2	II.3	III.2	III.4	III.5	III.6	IV.1	IV.2	Proband II
Diagnosis	MWS	MWS	MWS	MWS	MWS	MWS	MWS	MWS	MWS	MWS	FCAS
Age at onset (years)	0	0	1	0	0	1	1	0	0.5	2	3
Duration of crises (days)	3‐4	3‐4	3	2	3	3	2	1‐3	2‐3	2‐3	3
Frequency	>1/wk	2/mon	<1/mon	1/wk	1/wk	1‐4/mon	1/mon	1/mon	>1/mon	>1/mon	>2/mon
>3 crises	+	+	+	+	+	+	+	+	+	+	+
Triggers (Cold)	+	+	+	+	+	+	+	+	−	−	+

Abbreviation: FCAS, familial cold autoinflammatory syndrome; MWS, Muckle‐Wells syndrome.